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藥靶細胞株 > kinase激酶細胞株 > CBP73298c-Kit L576P/BaF3
- 詳細內(nèi)容
CBP73298 | |
I. Introduction | |
Cell Line Name: | c-Kit L576P/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
KIT L576P lies within the juxtamembrane domain (exon 11) of the Kit protein (PMID: 17372901). L576P confers a gain of function to Kit, as indicated by constitutive phosphorylation of Kit, and is transforming in cell culture (PMID: 17372901). | |
III. Representative Data | |
1. WB of c-Kit L576P/BaF3 | |
2. Sanger of c-Kit L576P/BaF3 | |
3. Anti-proliferation assay | |
| |
Figure 3. CTG Proliferation Assay of BaF3 c-KIT L576P (C6). |