懂色一区二区三区久久久,成人高清无码视频,中文字幕只是让你摩擦一下,国产精品人人爽人人做Av片

加入收藏 | 設(shè)為首頁(yè) | 聯(lián)系我們

產(chǎn)品搜索

產(chǎn)品分類(lèi)

聯(lián)系我們

聯(lián)系人:蔣經(jīng)理
電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com

產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73186EML4-ALK V3b/BaF3

EML4-ALK V3b/BaF3
名稱(chēng) EML4-ALK V3b/BaF3
型號(hào) CBP73186
報(bào)價(jià)
特點(diǎn) EML4-ALK V3b/BaF3,母細(xì)胞:BaF3,凍存條件:90% FBS+10% DMSO
  • 詳細(xì)內(nèi)容


CBP73186
I. Introduction

Cell Line Name:

EML4-ALK V3b/BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10% FBS+2ug/ml puromycin

Mycoplasma Status:

Negative


II.Background

Approximately 3–7% of lung tumors harbor ALK fusions (Koivunen et al. 2008; Kwak et al. 2010; Shinmura et al. 2008; Soda et al. 2007; Takeuchi et al. 2008; Wong et al. 2009). ALK fusions are more commonly found in light smokers (< 10 pack years) and/or never-smokers (Inamura et al. 2009; Koivunen et al. 2008; Kwak et al. 2010; Soda et al. 2007; Wong et al. 2009). ALK fusions are also associated with younger age (Inamura et al. 2009; Kwak et al. 2010; Wong et al. 2009) and adenocarcinomas with acinar histology (Inamura et al. 2009; Wong et al. 2009) or signet-ring cells (Kwak et al. 2010). Clinically, the presence of EML4-ALK fusions is associated with EGFR tyrosine kinase inhibitor (TKI) resistance (Shaw et al. 2009).

Multiple different ALK rearrangements have been described in NSCLC. The majority of these ALK fusion variants are comprised of portions of the echinoderm microtubule-associated protein-like 4 (EML4) gene with the ALK gene. At least nine different EML4-ALK fusion variants have been identified in NSCLC (Figure 1; Choi et al. 2008; Horn and Pao 2009; Koivunen et al. 2008; Soda et al. 2007; Takeuchi et al. 2008; Takeuchi et al. 2009; Wong et al. 2009). In addition, non-EML4 fusion partners have also been identified, including KIF5B-ALK (Takeuchi et al. 2009) and TFG-ALK (Rikova et al. 2007). Clinically, the presence of an ALK rearrangement is detected by fluorescence in situ hybridization (FISH) with an ALK break apart probe. FISH testing is not able to discern which particular ALK fusion is found in a clinical sample.


III. Representative Data

1. WB of EML4-ALK V3b/BaF3 expression

CBP73186 WB.jpg

Figure 1. WB of ALK expression

2. Anti-proliferation assay


Figure 2. Anti-proliferation assay of three reference compounds on the EML4-ALK V3b/BaF3 Stable Cell Line




如果你對(duì)CBP73186EML4-ALK V3b/BaF3感興趣,想了解更詳細(xì)的產(chǎn)品信息,填寫(xiě)下表直接與廠家聯(lián)系:


留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細(xì)地址:

  • 補(bǔ)充說(shuō)明:

  • 驗(yàn)證碼:

    請(qǐng)輸入計(jì)算結(jié)果(填寫(xiě)阿拉伯?dāng)?shù)字),如:三加四=7

化工儀器網(wǎng)

推薦收藏該企業(yè)網(wǎng)站
久久久久精品| 熟女精品69导航| 月婷婷中文字幕| 国产亚洲欧洲996久久综合| 国产日韩欧美二区| 蜜桃97成熟w| 天海翼一区| 中文字幕 在线综合| 德阳市| 特黄片大学生特黄片| 欧美黑人肉体狂欢交换大派对| 亚洲欧美日本一区二区| 国产99久久久久久免费看| 日韩一区二区三区四区成人电影| 精品国产免费一区二区三区| 男生操男生网站| 91人妻无码一区二区三区| 女同av在线| swag国产精品| 国产成人精品免费视频大全| 日欧高清无码一区二区三区| 深夜视频在线看你懂的| 丁香五月综合激情四射| 精品无码av一区二区| 欧美深喉精品国产精品| 体内精69xxxxxx白浆| 成熟丰满熟妇AV无码区五季| 亚洲无限吗在线看| 少妇性饥渴A区无码免费| 亚洲第一视频在线观看高清| 日韩欧美精品一区二区w| 在线精品_黑人va| 超碰国| 另类男人天堂网| 996热在线观看| 欧美亚洲另类一区| 熟妇一二区| 色哥哥| 日韩精品v| 天堂中文在线资| 殴美666666|