名稱 | PDGFRA D842V-T674I/BaF3 kinase細(xì)胞株 |
型號(hào) | CBP73335 |
報(bào)價(jià) | |
特點(diǎn) | PDGFRA D842V-T674I/BaF3 |
產(chǎn)品搜索
相關(guān)文章
聯(lián)系我們
電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73335PDGFRA D842V-T674I/BaF3 kinase細(xì)胞株
- 詳細(xì)內(nèi)容
CBP73335 | |
I. Introduction | |
Cell Line Name: | PDGFRA D842V-T674I/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
PDGFRA D842V lies within the protein kinase domain of the Pdgfra protein (UniProt.org). D842V results in ligand-independent phosphorylation of Pdgfra, activation of downstream signaling, and is transforming in culture (PMID: 22745105, PMID: 23752188, PMID: 29533785, PMID: 30253204) and confers resistance to PDGFRA inhibitors (PMID: 30389923, PMID: 18955458). | |
III. Representative Data | |
1.Sanger of PDGFRA D842V-T674I/BaF3 Figure 1. PDGFRA D842V-T674I/BaF3 T674I Figure 2. PDGFRA D842V-T674I/BaF3 D842V | |
2. Anti-proliferation assay | |
Figure 3. CTG Proliferation Assay of BaF3 PDGFRA D842V/T674I Cells (C4). |