名稱 | CXCR1/CHO GPCR細(xì)胞 |
型號 | CBP71360 |
報(bào)價(jià) | |
特點(diǎn) | CXCR1/CHO |
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電話:4008750250
號碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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藥靶細(xì)胞株 > GPCR細(xì)胞株 > CBP71360CXCR1/CHO GPCR細(xì)胞
- 詳細(xì)內(nèi)容
CBP71360 | |
I. Background | |
CXCR1 (C-X-C Motif Chemokine Receptor 1) is a Protein Coding gene.The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. | |
II. Introduction | |
Host Cell: | CHO |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12K+10%FBS+5ug/ml puromycin |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): | Functional assay for CXR1 receptor |
Transducer: | Gi |
Ⅲ. Description of Host Cell Line | |
Organism: | Hamster |
Tissue: | Ovary |
Morphology: | Epithelial |
Growth Properties: | Adherent |
Ⅳ. Representative Data | |
Figure 1. Recombinant CXCR1/CHO constitutively expressing CXCR1. | |
Figure 2. IL-8 efffect on CHO-CXCR1 clone 6. |