名稱 | EZH2 p.Y646F Reference Standard 標準品 |
型號 | CBP10276 |
報價 | |
特點 | EZH2 p.Y646F Reference Standard |
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聯(lián)系人:蔣經(jīng)理
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Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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CBP10276 | |
Format | Genomic DNA |
Description | EZH2 Y646F (corresponds to Y641F in the canonical isoform) lies within a SET domain of the Ezh2 protein (UniProt.org). Y646F confers a gain of function to the Ezh2 protein, as demonstrated by altered substrate specificity and increased catalytic efficiency for H3K27 trimethylation (PMID: 21190999, PMID: 24563539). |
Technical Data | |
DNA Change | c.1937A>T |
AA Change | p.Y646F |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 33.33% |
Transcript | ENST00000320356 |
Cosmic ID | COSM37028 |
Chr position(GRCh37) | chr7:148508727 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |