名稱 | AI-Edigene® ERBB2 p.A775_G776insYVMA Referenc |
型號 | CBP10416 |
報(bào)價(jià) | |
特點(diǎn) | AI-Edigene® ERBB2 p.A775_G776insYVMA Reference Standard Plus |
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Email: zhangxiangwen@cobioer.com
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10416AI-Edigene® ERBB2 p.A775_G776insYVMA Referenc
- 詳細(xì)內(nèi)容
CBP10416 | |
Format | Genomic DNA |
Description | ERBB2 (HER2) A775_G776insYVMA results in the insertion of four amino acids in the protein kinase domain of the Erbb2 (Her2) protein between amino acids 775 and 776 (UniProt.org). A775_G776insYVMA results in the same amino acid change as M774_A775insAYVM, which leads to constitutive phosphorylation of Erbb2 (Her2) and is transforming in cell culture (PMID: 17311002, PMID: 29967253). |
Technical Data | |
DNA Change | c.2324_2325ins12 ATACGTGATGGC |
AA Change | p.A775_G776insYVMA |
Mutation type | Insertion - In frame |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000269571 |
Cosmic ID | COSM20959 |
Chr position(GRCh37) | chr17:37880995_37880996 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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