名稱 | AI-Edigene® ERBB2 p.V777_G778insCG Reference |
型號 | CBP10474 |
報(bào)價(jià) | |
特點(diǎn) | AI-Edigene® ERBB2 p.V777_G778insCG Reference Standard Plus |
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號碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10474AI-Edigene® ERBB2 p.V777_G778insCG Reference
- 詳細(xì)內(nèi)容
CBP10474 | |
Gene | ERBB2 |
Description | ERBB2 (HER2), erb-b2 receptor tyrosine kinase 2, is an EGFR receptor tyrosine kinase that activates PI3K-AKT-mTOR and RAS-RAF-MEK-ERK pathways, therefore regulating growth and transformation (PMID: 17471238). ERBB2 (HER2) amplification, overexpression, and activation has been implicated in several tumor types (PMID: 17471238). |
Technical Data | |
DNA Change | c.2331_2332insTGTGGG |
AA Change | p.V777_G778insCG |
Mutation type | In_Frame_Ins |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | NM_004448.3 |
Cosmic ID | N/A |
Chr position(GRCh37) | chr17:37881002_37881003 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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