名稱 | AI-Edigene® FGFR3 p.S249C Reference Standard |
型號(hào) | CBP10553 |
報(bào)價(jià) | |
特點(diǎn) | AI-Edigene® FGFR3 p.S249C Reference Standard Plus |
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號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10553AI-Edigene® FGFR3 p.S249C Reference Standard
- 詳細(xì)內(nèi)容
CBP10553 | |
Format | Genomic DNA |
Description | FGFR3, fibroblast growth factor receptor 3, is a receptor tyrosine kinase activated upon binding of the FGF ligand, which activates RAS-MAPK and PI3K-AKT pathways (PMID: 22508544). Altered function of FGFR3 in cancer may lead to increased cell proliferation and decreased apoptosis (PMID: 22508544) and mutations and fusions are commonly observed in bladder cancer (PMID: 30975452, PMID: 23175443). |
Technical Data | |
DNA Change: | c.746C>G |
AA Change | p.S249C |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | NM_000142.5 |
Cosmic ID | COSM715 |
Chr position(GRCh37) | chr4:1803568 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purity | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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