名稱 | Her2 WT/BaF3 |
型號 | CBP73110 |
報價 | |
特點 | Her2 WT/BaF3,母細胞:BaF3,凍存條件:90% FBS+10% DMSO |
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藥靶細胞株 > kinase激酶細胞株 > CBP73110Her2 WT/BaF3
- 詳細內(nèi)容
CBP73110 | |
I. Introduction | |
Cell Line Name: | Her2 WT/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10% FBS |
Mycoplasma Status: | Negative |
II.Background | |
ERBB2 (HER2), erb-b2 receptor tyrosine kinase 2, is an EGFR receptor tyrosine kinase that activates PI3K-AKT-mTOR and RAS-RAF-MEK-ERK pathways, therefore regulating growth and transformation (PMID: 17471238). ERBB2 (HER2) amplification, overexpression, and activation has been implicated in several tumor types (PMID: 17471238). | |
III. Representative Data | |
1. WB of Her2 WT/BaF3 | |
2. Anti-proliferation assay | |
Figure 2. Anti-proliferation assay of two reference compounds on the Ba/F3_HER2 WT Stable Cell line. |